Analysis of survival data in thalassemia patients in Shiraz, Iran / 한국역학회지
Epidemiology and Health
;
: e2015031-2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-721218
ABSTRACT
OBJECTIVES:
The survival rate of thalassemia patients has not been conclusively established, and the factors associated with survival remain unclear. This study aimed to determine the survival rate of thalassemia among patients in southern Iran and to identify the factors associated with mortality from thalassemia.METHODS:
This retrospective cohort study was conducted based on a retrospective review of the medical records of 911 beta-thalassemia patients in 2014. Data analysis was conducted using the Kaplan-Meier method and Cox regression analysis.RESULTS:
Overall, 212 patients (23.3%) died, and 26.8% had thalassemia intermedia. The 20-year, 40-year, and 60-year survival rates were 85%, 63%, and 54%, respectively. Both crude and adjusted analyses found that education, marital status, ferritin levels, and comorbidities were related to mortality.CONCLUSIONS:
Sociodemographic and hematological factors were found to be significantly associated with the survival rate of thalassemia. Addressing these factors may help healthcare providers and physicians to provide the best possible care and to improve the survival rate.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Talasemia
/
Comorbilidad
/
Registros Médicos
/
Tasa de Supervivencia
/
Estudios Retrospectivos
/
Estadística como Asunto
/
Estudios de Cohortes
/
Mortalidad
/
Personal de Salud
/
Estado Civil
Tipo de estudio:
Estudio de etiología
/
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
Límite:
Humanos
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Epidemiology and Health
Año:
2015
Tipo del documento:
Artículo
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