Attunement Disorder : A Disorder of Brain Connectivity
Journal of the Korean Society of Biological Psychiatry
;
: 136-143, 2013.
Artículo
en Coreano
| WPRIM
| ID: wpr-725005
ABSTRACT
OBJECTIVES:
We reviewed cellular and synaptic dysconnectivity, disturbances in micro- and macro- circuitries, and neurodevelopmentally-derived disruptions of neural connectivity in the pathogenesis of schizophrenia.METHOD:
We reviewed the selected articles about disturbances in neural circuits which had been proposed as a pathogenetic mechanism of schizophrenia.RESULTS:
The literature review reveals that schizophrenia may be a disease related to disturbance in neurodevelopmental mechanism, shown as 'a misconnection syndrome of neural circuit or neural network'. In descriptive psychopathological view, definition of a disorder of brain connectivity has limitation to explain other aspects of schizophrenia including deterministic strictness in thought process.CONCLUSION:
Schizophrenia is considered as a disorder of brain connectivity as well as a neurodevelopmental disorder related with genetic and environmental factors. We could make a suggestion that "JoHyeonByung (attunement disorder)" denotes the disturbances of psychic fine-tuning which correspond to the neural correlates of brain dysconnectivity metaphorically.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Esquizofrenia
/
Encéfalo
/
Metáfora
Idioma:
Coreano
Revista:
Journal of the Korean Society of Biological Psychiatry
Año:
2013
Tipo del documento:
Artículo
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