Treatment Strategies for Psychotic Depression
Journal of the Korean Society of Biological Psychiatry
;
: 234-243, 2006.
Artículo
en Coreano
| WPRIM
| ID: wpr-725158
ABSTRACT
OBJECTIVES:
Several factors, such as biological markers, clinical correlates, and course of the depressive disorders with psychotic symptoms differ from those without psychotic symptoms. Therefore, specification of a treatment algorithm for depressive disorder with psychotic symptoms is legitimated. This article provides a systematic review of somatic treatments for depressive disorder with psychotic symptoms.METHODS:
According to the search strategy of the Clinical Research Center for Depression of Korean Health 21 R & D Project, first, PubMed and EMBASE were searched using terms with regard to the treatment of depressive disorders with psychotic symptoms(until July 2006). Reference lists of related reviews and studies were searched. In addition, relevant practice guidelines were searched using PubMed. All identified clinical literatures were reviewed and summarized in a narrative manner.RESULTS:
Treatment options, such as a combination of an antidepressant and an antipsychotic versus an antidepressant or an antipsychotic alone are summarized. In addition, issues regarding the electroconvulsive therapy(ECT), combination therapy, and maintenance treatment are discussed.CONCLUSION:
In former times, the combination of an antidepressant and an antipsychotic or ECT were recommended as the first line treatment for depressive disorder with psychotic symptoms. Recently, however, there was a suggestion that there was no conclusive evidence that the combination of an antidepressant and an antipsychotic drug is more effective than an antidepressant alone. More evidence regarding the pharmacological treatment for depressive disorder with psychotic symptoms is needed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Biomarcadores
/
Depresión
/
Trastorno Depresivo
Tipo de estudio:
Guía de Práctica Clínica
/
Estudio pronóstico
Idioma:
Coreano
Revista:
Journal of the Korean Society of Biological Psychiatry
Año:
2006
Tipo del documento:
Artículo
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