Glycemic Targets for the Critically Ill Patient / 임상당뇨병
Journal of Korean Diabetes
; : 18-24, 2015.
Article
en Ko
| WPRIM
| ID: wpr-726988
Biblioteca responsable:
WPRO
ABSTRACT
Critically ill patients often experience hyperglycemia, which may be associated with increased morbidity and mortality. In 2001, van den Berghe et al. suggested significant benefit of normalization of blood glucose level in critically ill patients using intensive intravenous insulin therapy. Subsequent multicenter randomized studies, however, demonstrated adverse effects of tight glucose control. Therefore, while the need for glucose control in critically ill patients is generally accepted, the treatment thresholds for initiation of insulin therapy or target glucose values are still undetermined. Furthermore, occurrence of a hypoglycemic event during intensive insulin therapy is known to be an independent predictor of clinical outcome, and glycemic variability is an important variable of glucose management in the critically ill patients. Novel technological approaches such as a continuous glucose monitoring system (CGMS) might help to overcome some problems of tight glucose control by reducing the risk of hypoglycemia and minimizing glycemic variability.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Glucemia
/
Mortalidad
/
Enfermedad Crítica
/
Glucosa
/
Hiperglucemia
/
Hipoglucemia
/
Insulina
/
Unidades de Cuidados Intensivos
Tipo de estudio:
Clinical_trials
/
Prognostic_studies
Límite:
Humans
Idioma:
Ko
Revista:
Journal of Korean Diabetes
Año:
2015
Tipo del documento:
Article