Effects of Smoking Cessation on Airflow Obstruction and Quality of Life in Asthmatic Smokers
Allergy, Asthma & Immunology Research
;
: 254-259, 2010.
Artículo
en Inglés
| WPRIM
| ID: wpr-72905
ABSTRACT
PURPOSE:
Smoking elicits airway inflammation and airflow obstruction in patients with asthma, even after smoking cessation. The aim of this study was to examine the effects of smoking cessation on lung function and quality of life (QOL) in asthmatic patients.METHODS:
Thirty-two patients with asthma who were active smokers were recruited. After education on the effects of smoking on asthma, 22 patients continued to smoke, and 10 quit smoking. All patients were treated with inhaled fluticasone propionate (1 mg/day) for 3 months. We compared forced expiratory volume in 1 s (FEV1), FEV1/forced vital capacity (FVC), forced expiratory flow between 25 and 75% FVC (FEF(25-75%)), and scores on a QOL questionnaire at baseline, 1, 2, and 3 months.RESULTS:
Quitters showed a greater percent change in FEV1 (19.1+/-6.3 vs. 7.9+/-2.4%, P=0.024) and FEV1/FVC (6.5+/-4.14 vs. 3.5+/-1.5%, P=0.05) than smokers. Both quitters and smokers showed improved QOL scores after 1, 2, and 3 months of fluticasone treatment.CONCLUSIONS:
Patients with asthma who quit smoking showed less airway obstruction, suggesting that smoking cessation is crucial in the management of asthma.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Calidad de Vida
/
Asma
/
Humo
/
Fumar
/
Capacidad Vital
/
Volumen Espiratorio Forzado
/
Encuestas y Cuestionarios
/
Cese del Hábito de Fumar
/
Obstrucción de las Vías Aéreas
/
Dietilpropión
Límite:
Humanos
Idioma:
Inglés
Revista:
Allergy, Asthma & Immunology Research
Año:
2010
Tipo del documento:
Artículo
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