Hypoglycemic Effects of Exo-biopolymers Produced by Five Different Medicinal Mushrooms in STZ-induced Diabetic Rats
Mycobiology
;
: 45-49, 2008.
Artículo
en Inglés
| WPRIM
| ID: wpr-729561
ABSTRACT
Hypoglycemic effects of exo-biopolymers (EBP) produced by submerged mycelial cultures of Coriolus versicolor, Cordyceps sinensis, Paecilomyces japonica, Armillariella mellea, and Fomes fomentarius were investigated in streptozotocin (STZ)-induced diabetic rats. The rats from each experimental group were orally administered with EBPs (100 mg/kg BW) daily for 2 weeks. Though the hypoglycemic effect was achieved in all the cases, however, C. versicolor EBP proved as the most potent one. The administration of the C. versicolor EBP substantially reduced (29.9%) the plasma glucose level as compared to the saline administered group (control). It also reduced the plasma total cholesterol (TC), triglyceride (TG), aspartate aminotransferase (AST) and, alanine aminotransferase (ALT) levels by 9.22, 23.83, 16.93, and 27.31%, respectively. The sugar and amino acid compositions of this EBP were also analyzed in detail.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Plasma
/
Aspartato Aminotransferasas
/
Paecilomyces
/
Colesterol
/
Estreptozocina
/
Cordyceps
/
Agaricales
/
Alanina Transaminasa
/
Coriolaceae
/
Glucosa
Límite:
Animales
Idioma:
Inglés
Revista:
Mycobiology
Año:
2008
Tipo del documento:
Artículo
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