Research Progress in Citrulline and Related Diseases / 沈阳医学院学报

ABSTRACT

Citrulline which is a nonprotein amino acid,synthesizes the peptide bond,but it is not incorporated into proteins. It's used to be known as no point, but there is a difficult result that citrulline is related to many diseases in recent research.Citrulline is a biomaker in gastrointestinal injury,a supplement of arginine in arginine deficiency patients,and the evidence of sepsis.Citrulline,as an antigen among the process of its creation ,is one of the nosogenesis of rheumatoid arthritis,and checking the antibodies of citrulline is effective in diagnosing the rheumatoid arthritis early. Citrulline is also meaningful in diagnosing and treatment of some unfrequent diseases. Citrulline is widely used.