Blistering Eruption and Fulminant Hepatitis: A Fatal Coinfection of Leptospirosis and Disseminated Herpes Simplex

ABSTRACT

Leptospirosis has a wide spectrum of nonspecific clinical manifestations ranging from mild diseaseto multiorgan failure with variable cutaneous manifestations. Disseminated herpes simplex virusinfection usually occurs in the setting of immunosuppression. Both these infections are rare infectivecauses of fulminant hepatitis. Herein, we report a case of fatal leptospirosis and disseminated herpessimplex virus coinfection, in the hopes that this report will increase awareness among health careproviders for relevant investigation and prompt management.