Research advance in children's orthostatic hypertension / 中华实用儿科临床杂志

ABSTRACT

Orthostatic hypertension (OHT) is defined as an increase in blood pressure from supine to orthostatic position.Its mechanism involves a greater venous pooling in the lower extremities,sympathetic activation,change of neurohumoral factors and hypersensitivity of baroreflex.The diagnosis of OHT mainly depends on head-up tilt test.OHT is closely related to hypertension,coronary artery diseases and asymptomatic cerebral infarction.It might be a new predictor of cardiovascular and cerebrovascular diseases and a long-term marker for evaluating target organs damage in hypertension.Studies about OHT in children are rare.To some extent,blood pressure exists tracking phenomenon,further study of OHT in children is beneficial to predict the risk of cardiovascular and cerebrovascular disease and evaluate the target organ damage in adulthood.