Anti-inflammatory Effect of Bumblebee Alcohol Extracts in CFA-Induced Rat Edema
Toxicological Research
;
: 249-253, 2012.
Artículo
en Inglés
| WPRIM
| ID: wpr-73345
ABSTRACT
In this study, we prepared alcohol extracts of the larva, pupa, queen, and cocoon (clony) of B. ignitus, B. terrestris, and B. h. sapporoensis, and tested the anti-inflammatory activity of the extracts by using a rat model of adjuvant-induced edema. The extracts derived from the queen of B. ignitus, the queen of B. terrestris, and the cocoon of B. ignitus decreased hind paw edema after 1 day of i.p. administration. These extracts also induced vasorelaxation and NO production in calf pulmonary artery endothelial cells. These results suggest that bumblebee alcohol extracts has anti-inflammatory and vasorelaxant properties.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Arteria Pulmonar
/
Pupa
/
Vasodilatación
/
Células Endoteliales
/
Edema
/
Larva
Límite:
Animales
Idioma:
Inglés
Revista:
Toxicological Research
Año:
2012
Tipo del documento:
Artículo
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