Analysis of risk factors of the first time of esophageal varices bleeding in cirrhosis / 中国基层医药

ABSTRACT

Objective To analyze the risk factors of the first time of upper gastrointestinal tract variceal bleeding in patients with liver cirrhosis,and to provide suggestions and references for targeted nursing strategies.Methods From January 2016 to December 2017,86 cases of liver cirrhosis for the first time of upper gastrointestinal tract variceal bleeding treated in Shaoxing Municipal Hospital were randomly selected as bleeding group,and 86 patients with liver cirrhosis without upper gastrointestinal tract variceal bleeding were randomly selected as non-bleeding group.The retrospective investigation method was used,and SPSS 22.0 software was used for statistical analysis.Results The results of single factor analysis showed that there were significant differences in the incidence of upper gastrointestinal tract variceal bleeding in patients of liver cirrhosis with different course of disease (t =4.975,P ＜ 0.001),liver function (x2 =12.450,P =0.002),platelet count (t =2.243,P =0.012),prothrombin time (t =5.832,P ＜ 0.001),degree of esophageal varices (x2 =18.702,P ＜ 0.001),red sign (x2 =4.691,P =0.030) and portal vein diameter(t =3.425,P ＜0.001).The multivariate logistic regression analysis showed that the risk factors for the first time of upper gastrointestinal tract variceal bleeding were prothrombin time (OR =2.167,P ＜ 0.001),platelet count(OR =0.645,P =0.014),esophageal varicosity (OR =2.751,P =0.009) and portal vein diameter (OR =1.185,P =0.018).Conclusion Different factors are related to upper gastrointestinal tract variceal bleeding for the first time in patients with liver cirrhosis,and the medical staff should take corresponding nursing measures.