Effects of N-methyl-D-aspartate on the cochlear potentials / 第二军医大学学报
Academic Journal of Second Military Medical University
; (12): 1126-1129, 2001.
Article
en Zh
| WPRIM
| ID: wpr-735416
Biblioteca responsable:
WPRO
ABSTRACT
Objective: To study the effects of TNFα on wound healing. Methods: The skin lesion and incisions were made on mice and rhTNFα was applied in both skin lesion and incision. Tissue strips were evaluated for tensiometry and histologic features after healing. Results: It was found that rhTNFα markedly improved wound healing both in skin lesion and incision wound model, it also markedly enhanced the breaking strength of treated incision and increased wound cellularity in rh TNF α treated groups. Conclusion: The results suggest that TNFα play an important role in regulating inflammatory reactions of local injured tissues and it may improve the functions of fibroblasts, mononuclear phagocytes and endothelial cells. rhTNFα of suitable doses can promote wound healing. This shows that TNFα, as a wound healing promoter, has the potentials for clinical application.
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1
Índice:
WPRIM
Idioma:
Zh
Revista:
Academic Journal of Second Military Medical University
Año:
2001
Tipo del documento:
Article