Meta-analysis of HIV infection incidence and risk factors among men who have sex with men in ;China / 中华流行病学杂志

ABSTRACT

Objective To understand the incidence of HIV infection among men who have sex with men (MSM) in China. Methods Meta-analysis was performed to systematically and quantitatively review all the original research papers and reports published during 2010-2015 on the incidence of HIV infection among MSM in China. Pooled incidence,pooled hazard ratios,publication bias,heterogeneity and sensitivity analysis for those studies were calculated or analyzed by using Stata 12.0 software. Results A total of 24 studies were analyzed. Pooled incidence of HIV infection among MSM in China was 5.0/100 person year;Based on HIV case report,severe epidemic areas had higher HIV incidence than other areas(4.9/100 person year vs. 3.4/100 person year). Low education level(HR=1.61,95%CI1.21-2.15),syphilis prevalence(HR=3.22,95%CI2.21-4.70),unprotected anal sex(HR=2.92,95%CI1.51-5.63),minority ethnic group(HR=4.01,95%CI1.96-8.21), commercial sex(HR=4.11,95%CI1.47-11.46) and multiple sexual partners(HR=2.31,95%CI1.60-3.34)were the risk factors for HIV incidence. Conclusion Pooled incidence of HIV infection among MSM was 5.0% in China. Low education level,syphilis prevalence,unprotected anal sex, minority ethnic group,commercial sex and multiple sexual partners were the risk factors for HIV infection.