Clinical significance of plasma α1-antichymotrypsin in children with asthma / 第三军医大学学报
Journal of Third Military Medical University
;
(24): 356-357, 2001.
Artículo
en Chino
| WPRIM
| ID: wpr-736970
ABSTRACT
Objective To study the role of α1-antichymotrypsin(α1-ACT)in the pathogenesis of childhood asthma for providing a theoretical base for prevention and treatment of childhood asthma. Methods Levels of plasma α1-ACT in 30 asthmatic children and 30 healthy children were determined by rocket immunoelectrophoresis. Results Plasma α1-ACT levels were higher in acute phase than in paroxysmal phase [(0.4178±0.0815)vs(0.2865±0.0799), t=6.301,P<0.001] and also higher in asthma group than in control group [(0.4178±0.0815)vs(0.2876±0.0496),t=7.474,P<0.001]. The plasma α1-ACT levels in asthma group and control of paroxysmal phase were similor [(0.2865±0.0799) vs (0.2876±0.0496),t=0.064, P>0.05]. The levels of plasma α1-ACT were higher in moderate and heavily attacked patients than that in mild attacked patients [(0.4553±0.0758) vs (0.3249±0.0926),t=4.187,P<0.001] and those in control group [(0.4553±0.0758) vs (0.2865±0.0799),t=9.38,P<0.001]. Conclusion α1-ACT is involved in pathophysiological course of childhood asthma. Measurement of plasma α1-ACT levels may be helpful in determining the state of the illness and to evaluate the severity and treatment of childhood asthma.
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Third Military Medical University
Año:
2001
Tipo del documento:
Artículo
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