Clinical and laboratory features of the pulmonary aspergillosis in the Respiratory Department of Bach Mai Hospital

ABSTRACT

Introduction: Nowadays, the pulmonary mycosis is becoming more and more frequent because of the increase in risk factors. Pulmonary aspergillus is not an uncommon disease, but it often comes together with other lung diseases so it is easily missed. Objectives: This study aims to 1. Determine the clinical and laboratory characteristics of pulmonary mycosis. 2. Comment on the results of the treatment. Material and method: 15 patients with symptoms and signs of pulmonary aspergillosis were included in a retrospective study. Patients were given blood tests, sputum cytology, flexible bronchoscopy, chest X-ray and Ct scanner, transbronchial biopsy and transthoracic biopsy. Findings from these studies showed Aspergillus pulmonary mycosis. The patients were treated in Respiratory Department of Bach Mai hospital in 2007. Results: Male 7 cases, female 8 cases. Hemoptysis 9 cases (60%). 12 cases (80%) had definitive diagnosis, while 5 cases were confirmed diagnosis by transbronchial and/or transthoracic biopsy. 7 cases were treated by surgery. Conclusion: Pulmonary mycosis often occurs in patients with immunodeficiency or pulmonary cavities secondary to tuberculosis. The most common symptom of pulmonary mycosis is hemoptysis. Surgery is the most effective treatment for aspergilloma, as well as antifungal therapy for immunodeficiency patients.