Poorly Differentiated Neuroendocrine Carcinoma of the Eyelid
Journal of the Korean Ophthalmological Society
; : 861-866, 2018.
Article
en Ko
| WPRIM
| ID: wpr-738580
Biblioteca responsable:
WPRO
ABSTRACT
PURPOSE: To report a case of poorly differentiated neuroendocrine carcinoma of the eyelid. CASE SUMMARY: A 70-year-old male presented with a 5-month history of a right upper eyelid mass. The mass appeared as 1.2 × 1.2 cm on the right upper eyelid. A mass excision was performed under frozen section control. The tumor was completely excised with a safety margin clearance and an upper eyelid reconstruction was performed. Histopathological examination revealed a tumor composed of small atypical cells which showed a high nuclear/cytoplasm ratio, nuclear molding, and increased mitotic activity. Immunohistochemical examination revealed positive reactivity for Ki-67, synaptophysin, CD56, and negative reactivity for chromogranin, cytokeratin 20, and thyroid transcription factor-1. CONCLUSIONS: Primary neuroendocrine carcinoma of the eyelid is extremely rare, but the tumor has high malignancy and readily metastasizes. Poorly differentiated neuroendocrine carcinoma should be considered in the differential diagnosis of a rapidly growing eyelid mass.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Glándula Tiroides
/
Carcinoma de Células de Merkel
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Sinaptofisina
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Carcinoma de Células Pequeñas
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Carcinoma Neuroendocrino
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Diagnóstico Diferencial
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Queratina-20
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Párpados
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Secciones por Congelación
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Hongos
Tipo de estudio:
Diagnostic_studies
Límite:
Aged
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Humans
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Male
Idioma:
Ko
Revista:
Journal of the Korean Ophthalmological Society
Año:
2018
Tipo del documento:
Article