Poorly Differentiated Neuroendocrine Carcinoma of the Eyelid
Journal of the Korean Ophthalmological Society
;
: 861-866, 2018.
Artículo
en Coreano
| WPRIM
| ID: wpr-738580
ABSTRACT
PURPOSE:
To report a case of poorly differentiated neuroendocrine carcinoma of the eyelid. CASESUMMARY:
A 70-year-old male presented with a 5-month history of a right upper eyelid mass. The mass appeared as 1.2 × 1.2 cm on the right upper eyelid. A mass excision was performed under frozen section control. The tumor was completely excised with a safety margin clearance and an upper eyelid reconstruction was performed. Histopathological examination revealed a tumor composed of small atypical cells which showed a high nuclear/cytoplasm ratio, nuclear molding, and increased mitotic activity. Immunohistochemical examination revealed positive reactivity for Ki-67, synaptophysin, CD56, and negative reactivity for chromogranin, cytokeratin 20, and thyroid transcription factor-1.CONCLUSIONS:
Primary neuroendocrine carcinoma of the eyelid is extremely rare, but the tumor has high malignancy and readily metastasizes. Poorly differentiated neuroendocrine carcinoma should be considered in the differential diagnosis of a rapidly growing eyelid mass.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Glándula Tiroides
/
Carcinoma de Células de Merkel
/
Sinaptofisina
/
Carcinoma de Células Pequeñas
/
Carcinoma Neuroendocrino
/
Diagnóstico Diferencial
/
Queratina-20
/
Párpados
/
Secciones por Congelación
/
Hongos
Tipo de estudio:
Estudio diagnóstico
Límite:
Anciano
/
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of the Korean Ophthalmological Society
Año:
2018
Tipo del documento:
Artículo
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