A Case of Aggravation of Thyroid Goiter after Treatment with PD-1 Inhibitor for Breast Cancer in Patients with Underlying Hashimoto's Thyroiditis
International Journal of Thyroidology
;
: 172-175, 2018.
Artículo
en Coreano
| WPRIM
| ID: wpr-738940
ABSTRACT
Anti-programmed cell death-1 (PD-1) humanized monoclonal antibody inhibits PD-1 activity by binding to the PD-1 receptor on T-cells and blocking PD-1 ligands and induces immune tolerance of cancer cells. It has been widely used for various kinds of cancer treatment. However, many immune-related adverse events (irAEs) have been reported because it modulates our immune system. In this case study, we reported a case of 42-year-old woman with Hashimoto's thyroiditis who showed rapid aggravation of thyroid goiter and acute hyperventilation syndrome after treatment with PD-1 inhibitor as a neoadjuvant chemotherapy for breast cancer.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Glándula Tiroides
/
Tiroiditis
/
Mama
/
Neoplasias de la Mama
/
Linfocitos T
/
Quimioterapia
/
Receptor de Muerte Celular Programada 1
/
Bocio
/
Hiperventilación
/
Sistema Inmunológico
Límite:
Adulto
/
Femenino
/
Humanos
Idioma:
Coreano
Revista:
International Journal of Thyroidology
Año:
2018
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS