Change in the Prevalences and Risk Factors of Atrophic Gastritis and Intestinal Metaplasia in Korea: Multicenter Clinical Trials
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
;
: 247-257, 2018.
Artículo
en Coreano
| WPRIM
| ID: wpr-738981
ABSTRACT
BACKGROUND/AIMS:
The aim of this study was to analyze the trend of the prevalences of atrophic gastritis (AG) and intestinal metaplasia (IM) from 2011 to 2016~2017 in Korea. And, the risk factors of AG and IM were compared between 2011 and 2016~2017. MATERIALS ANDMETHODS:
A total of 4,023 subjects in 2011 and 2,506 subjects in 2016~2017 were enrolled. AG and IM were diagnosed on the basis of endoscopic findings. Multivariate analysis was performed for risk factors of AG and IM. Seventeen factors were analyzed.RESULTS:
The seroprevalence of Helicobacter pylori decreased from 2011 (59.8%; 2,407/4,023) to 2016~2017 (51.6%; 1,293/2,506; P < 0.001). The prevalence of AG decreased from 2011 to 2016~2017 (P=0.018), but that of IM increased (P < 0.001). The risk factors of AG in 2011 were male sex, old age, H. pylori immuoglobulin G (IgG) positivity, family history of gastric cancer (GC), and high-salt diet. For IM in 2011, the risk factors were male sex, old age, H. pylori IgG positivity, and family history of GC. Risk factors of AG in 2016~2017 were old age, H. pylori IgG positivity, and country of residence. For IM in 2016~2017, the risk factors were male sex, old age, family history of GC, high fasting glucose level (≥126 mg/dL), H. pylori IgG positivity, and low income level.CONCLUSIONS:
The difference in prevalence trends of AG and IM between 2016~2017 and 2011 could be the result of the different risk factors of AG and IM, such as decreased prevalence of H. pylori infection.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Neoplasias Gástricas
/
Inmunoglobulina G
/
Estudios Seroepidemiológicos
/
Prevalencia
/
Análisis Multivariante
/
Factores de Riesgo
/
Helicobacter pylori
/
Ayuno
/
Dieta
/
Gastritis Atrófica
Tipo de estudio:
Ensayo Clínico Controlado
/
Estudio de etiología
/
Estudio de prevalencia
/
Factores de riesgo
Límite:
Humanos
/
Masculino
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
The Korean Journal of Helicobacter and Upper Gastrointestinal Research
Año:
2018
Tipo del documento:
Artículo
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