Prognostic Factors in Premature Infants with Pulmonary Hemorrhage occuring after Surfactant Replacement
Journal of the Korean Society of Neonatology
;
: 162-170, 1999.
Artículo
en Coreano
| WPRIM
| ID: wpr-73934
ABSTRACT
PURPOSE:
Exogenous surfactant replacement therapy reduces morbidity and mortality rates for premature babies with respiratory distress syndrome (RDS). A significant increase in clinical pulmonary hemorrhage has been reported in premature babies treated with surfactant. Pulmonary hemorrhage, one of the major cause of death, may develop due to an increased pulmonary blood flow. We investigated the prognostic factors for mortality in premature infants with pulmonary hemorrhage after surfactant replacement, and to predict the survival of infants having RDS.METHODS:
We investigated the characteristics and clinical courses of the 22 premature infants who developed pulmonary hemorrhage after surfactant therapy for RDS hospitalized at Seoul Red Cross Hospital between Dec 1994 and May 1998. We divided the patients into two groups ' Group I were those who survived (n=6) and Group II were those who expired after pulmonary hemorrhage (n=16).RESULTS:
There were no differences in birth weight, gestational age and radiologic staging between two groups (P>0.05). Low Apgar score at birth was significantly related to mortality in premature infants with pulmonary hemorrhage (P<0.05). The interval between birth and onset of pulmonary hemorrhage and the interval between the surfactant replacement and onset of pulmonary hemorrhage were significantly longer in Group I than in Group II (P<0.05).CONCLUSION:
The clinical conditions at birth, the interval between birth and onset of pulmonary hemorrhage, and the interval between surfactant replacement and onset of pulmonary hemorrhage were the prognostic factors of mortality in preterm infants with pulmonary hemorrhage.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Puntaje de Apgar
/
Cruz Roja
/
Peso al Nacer
/
Recien Nacido Prematuro
/
Mortalidad
/
Causas de Muerte
/
Edad Gestacional
/
Parto
/
Seúl
/
Hemorragia
Tipo de estudio:
Estudio pronóstico
Límite:
Humanos
/
Lactante
/
Recién Nacido
País/Región como asunto:
Asia
Idioma:
Coreano
Revista:
Journal of the Korean Society of Neonatology
Año:
1999
Tipo del documento:
Artículo
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