Antimicrobial Effect of Ethanol Extract of Garcinia mangostana L. against Enterococcus faecalis Isolated from Human Oral Cavity
International Journal of Oral Biology
;
: 129-132, 2018.
Artículo
en Coreano
| WPRIM
| ID: wpr-740077
ABSTRACT
Enterococcus faecalis is a major causative agent of endodontic treatment failure. The purpose of this study was to investigate bactericidal effects of ethanol extract of Garcinia mangostana L. (mangosteen extract) on five strains of E. faecalis that were isolated from human oral cavities. The bactericidal effects of mangosteen extract were assessed by measurement of minimum bactericidal concentration (MBC) value. The cytotoxicity of mangosteen extract on immortalized human gingival fibroblasts, hTERT-hNOF, was determined based on cell counting method. The data revealed the MBC value of mangosteen extract against the E. faecalis strains was 4 µg/ml. Additionally, the cell viability of mangosteen extract on hTERT-hNOF was 83.7–89.1% at the 1 to 16 µg/ml. These findings indicated that mangosteen extract could be used as a root canal cleaner during management of endodontic treatment failure caused by E. faecalis.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Recuento de Células
/
Supervivencia Celular
/
Enterococcus
/
Enterococcus faecalis
/
Insuficiencia del Tratamiento
/
Garcinia
/
Garcinia mangostana
/
Cavidad Pulpar
/
Etanol
/
Fibroblastos
Límite:
Humanos
Idioma:
Coreano
Revista:
International Journal of Oral Biology
Año:
2018
Tipo del documento:
Artículo
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