Different invasion efficiencies of Brucella abortus wild-type and mutantsin RAW 264.7 and THP-1 phagocytic cells and HeLa non-phagocytic cells / 대한수의학회지
Korean Journal of Veterinary Research
;
: 95-98, 2018.
Artículo
en Inglés
| WPRIM
| ID: wpr-741500
ABSTRACT
Brucellosis is one of the common zoonoses caused by Brucella abortus (B. abortus). However, little has been reported on factors affecting invasion of B. abortus into host cells. To investigate cell-type dependent invasion of B. abortus, phagocytic RAW 264.7 and THP-1 cells and non-phagocytic HeLa cells were infected with wild-type and mutant B. abortus, and their invasion efficiencies were compared. The invasion efficiencies of the strains were cell-type dependent. Wild-type B. abortus invasion efficiency was greater in phagocytic cells than in epithelial cells. The results also indicated that there are different factors involved in the invasion of B. abortus into phagocytic cells.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Fagocitos
/
Brucella
/
Brucella abortus
/
Brucelosis
/
Células HeLa
/
Zoonosis
/
Células Epiteliales
Límite:
Humanos
Idioma:
Inglés
Revista:
Korean Journal of Veterinary Research
Año:
2018
Tipo del documento:
Artículo
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