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Diagnosis of an indistinct Leydig cell tumor by positron emission tomography-computed tomography
Obstetrics & Gynecology Science ; : 194-198, 2019.
Artículo en Inglés | WPRIM | ID: wpr-741748
ABSTRACT
A 51-year-old perimenopausal female patient presented with hirsutism and voice thickening which was started approximately one and a half years ago. Her initial hormone assay revealed elevated plasma testosterone, 5a-dihydrotestosterone, and dehydroepiandrosterone (DHEA) levels and therefore androgen-secreting tumor was first suspected. However, the lesion was inconspicuous on transvaginal sonography, abdominal-pelvic computed tomography (CT) scan, and pelvic magnetic resonance (MRI) imaging. Consequently, 18F-fluorodeoxyglucose (FDG) positron emission tomography-CT was performed, which localized the lesion as a focal FDG uptake within the right adnexa. Total laparoscopic hysterectomy with bilateral salpingo-oophorectomy was performed, and although visible gross mass lesions were not observed intraoperatively, pure Leydig cell tumor was pathologically confirmed within the right ovary. Plasma testosterone, 5a-dihydrotestosterone, and DHEA levels were normalized postoperatively. Clinical signs of virilization were also significantly resolved after 3-months of follow-up.
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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Ovario / Plasma / Testosterona / Virilismo / Voz / Estudios de Seguimiento / Deshidroepiandrosterona / Tumor de Células de Sertoli-Leydig / Diagnóstico / Electrones Tipo de estudio: Estudio diagnóstico / Estudio observacional / Estudio pronóstico Límite: Femenino / Humanos Idioma: Inglés Revista: Obstetrics & Gynecology Science Año: 2019 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Ovario / Plasma / Testosterona / Virilismo / Voz / Estudios de Seguimiento / Deshidroepiandrosterona / Tumor de Células de Sertoli-Leydig / Diagnóstico / Electrones Tipo de estudio: Estudio diagnóstico / Estudio observacional / Estudio pronóstico Límite: Femenino / Humanos Idioma: Inglés Revista: Obstetrics & Gynecology Science Año: 2019 Tipo del documento: Artículo