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ABSTRACT

PURPOSE:

Wilms tumor is the most common malignant renal tumor in children. We investigated the epidemiology, clinical features and treatment outcome of the children with Wilms tumor in Korea during the recent 10 years.

METHODS:

Two hundred forty six patients were enrolled between January 1991 and December 2000 from 26 major hospitals in Korea. The data regarding the clinical features including sex, age, pathologic type, prognostic factor and treatment outcome of patients were analyzed retrospectively by review of patient's medical records. Kaplan-Meier survival curves were constructed, The differences between groups were analyzed by log-rank test.

RESULTS:

There were 130 males and 116 females. The incidence between the age of 1~4 years was the highest with 66.2%. The annual incidence rate per 1, 000, 000 population varied from 1.9 to 2.1. The 10 years overall survival rate according to sex, clinical stage, pathologic type and relapse were as follows 88.6% in male, 90.9% in female, 100% in stage I, 94.7% in stage II, 92.1% in stage III, 63.4% in stage IV, 85.7% in stage V, 95.3% in favorable histology, 64.1% in unfavorable histology, 94.8% in non-relapse, and 40.9% in relapse. The relapse rate was 12%. The 10 years overall survival rate of 246 patients were 89.1%.

CONCLUSION:

Our results could provide the most recent and important clinical information on Wilms tumor of children in Korea.
Asunto(s)

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Recurrencia / Registros Médicos / Epidemiología / Incidencia / Tasa de Supervivencia / Estudios Retrospectivos / Resultado del Tratamiento / Tumor de Wilms / Estimación de Kaplan-Meier / Corea (Geográfico) Tipo de estudio: Estudio de incidencia / Estudio observacional / Estudio pronóstico / Estudio de tamizaje Límite: Niño / Femenino / Humanos / Masculino País/Región como asunto: Asia Idioma: Coreano Revista: Korean Journal of Pediatric Hematology-Oncology Año: 2004 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Recurrencia / Registros Médicos / Epidemiología / Incidencia / Tasa de Supervivencia / Estudios Retrospectivos / Resultado del Tratamiento / Tumor de Wilms / Estimación de Kaplan-Meier / Corea (Geográfico) Tipo de estudio: Estudio de incidencia / Estudio observacional / Estudio pronóstico / Estudio de tamizaje Límite: Niño / Femenino / Humanos / Masculino País/Región como asunto: Asia Idioma: Coreano Revista: Korean Journal of Pediatric Hematology-Oncology Año: 2004 Tipo del documento: Artículo