Conbercept intravitreal injection combined with EX-PRESS glaucoma drainage device implantation for NVG / 国际眼科杂志(Guoji Yanke Zazhi)

ABSTRACT

@#AIM: To observe the effect of EX-PRESS glaucoma drainage device implantation in treatment of neovascular glaucoma after intravitreal injection of conbercept injection.<p>METHODS: From January 2015 to January 2018, 37 patients(37 eyes)with neovascular glaucoma were randomly divided into experimental group and control group. Both groups were treated with conbercept injection into vitreous cavity before operation. EX-PRESS glaucoma drainage device implantation and trabeculectomy were selected in the experimental group and the control group, respectively. The success rate, best corrected visual acuity(BCVA), intraocular pressure, filtering bleb and complications were compared between the two groups.<p>RESULTS: At 12mo after operation, there was no significant difference in success rate, BCVA and successful filtering bleb between the two groups. There was significant difference in intraocular pressure between the two groups at different time points(<i>F</i>_group=10.0, <i>P</i>_group=0.003; <i>F</i>_time= 496.27, <i>P</i><0.0001). All complications were improved after symptomatic treatment. <p>CONCLUSION: EX-PRESS glaucoma drainage device implantation combined with conbercept vitreous injection in treatment of NVG, which has certain clinical value in reducing intraocular pressure and postoperative complications.