Progress of idiopathic membranous nephropathy on adolescents / 国际儿科学杂志

ABSTRACT

Idiopathic membranous nephropathy (IMN) is one of the pathological types of nephrotic syndrome.Besides secondary factors,such as immune system diseases,hepatitis and tumors,the etiology is still unclear.Recent studies have shown that the incidence of IMN is increasing year by year,and the age of onset is gradually younger.Adolescents have become a representative group of new IMN patients.Researches have showed that adolescent idiopathic membrane patients have mild clinical and pathological manifestations,good renal function,and good prognosis.Most patients have fertility requirements,and there are clinical concerns about the application of hormones and immunosuppressive agents.This paper reviews the progress on the clinicopathological manifestation,treatment and prognosis of adolescent IMN patients.