Diagnostic values of 99Tcm-MIBI SPECT /CT imaging and planar imaging semi-quantitative analysis in primary hyperparathyroidism / 中华内分泌外科杂志
Chinese Journal of Endocrine Surgery
;
(6): 17-21, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-743389
ABSTRACT
Objective To evaluate the diagnostic value of 99Tcm-MIBI SPECT/CT imaging and 99Tcm-MIBI planar imaging semi-quantitative analysis in primary hyperparathyroidism (PHPT).Methods A total of 89 patients were enrolled into this retrospective study.The diagnostic efficiencies of 99Tcm-MIBI SPECT/CT were compared with 9Tcm-MIBI planar scintigraphy and ultrasound,while the surgical pathology and the clinical follow-up results were considered as the standard.The region of interest extraction technique was used to measure and calculate the tumour to normal tissue ratios (T/NT) in the early and delayed phase of the planar scintigraphy,and the correlation between pathological type,PTH concentration and T/NT ratios was analyzed.Results The sensitivities and specificities of SPECT/CT,99Tcm-MIBI planar scintigraphy and ultrasound were 98.08%,88.46%,78.43%;82.93%,82.93%,58.82% respectively.There were statistically significant correlations between the pathological type and PTH concentration,early phase T/NT and delayed phase T/NT,and the correlation coefficients r were 0.741,0.642 and 0.729,respectively.Conclusions 99Tcm-MIBI SPECT/CT imaging is an effective method for diagnosis of PHPT,with higher clinical application value than 99Tcm-MIBI planar scintigraphy and ultrasound.The semi-quantitative analysis of 99Tcm-MIBI planar scintigraphy provides a new method for the differential diagnosis of PHPT.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
Idioma:
Chino
Revista:
Chinese Journal of Endocrine Surgery
Año:
2019
Tipo del documento:
Artículo
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