Application of vincristine-loaded platelet therapy in three dogs with refractory immune-mediated thrombocytopenia
Journal of Veterinary Science
;
: 127-130, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-74485
ABSTRACT
Three dogs presented with refractory immune-mediated thrombocytopenia (IMT). All patients failed to respond to prednisone, which is considered a mainstay of immunosuppressive therapy. Vincristine-loaded platelets (VLPs), which act selectively on mononuclear phagocytes,were introduced. After the VLPs were transfused, two dogs responded quickly withimproved clinical signs while the third dogwith recurrent IMT was euthanized due to its deteriorating condition. This case report describesthe efficacy of VLP therapy in refractory IMT patients.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Vincristina
/
Púrpura Trombocitopénica Idiopática
/
Transfusión de Plaquetas
/
Enfermedades de los Perros
/
Antineoplásicos Fitogénicos
Límite:
Animales
Idioma:
Inglés
Revista:
Journal of Veterinary Science
Año:
2015
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS