Progress in pathogenesis and early diagnosis of Parkinson's disease / 中国综合临床
Clinical Medicine of China
;
(12): 276-280, 2019.
Artículo
en Chino
| WPRIM
| ID: wpr-745000
ABSTRACT
Objective Parkinson's disease (PD) is a common degenerative disease of the central nervous system.The main pathological feature is the reduction of dopaminergic neurons,which induces motion symptoms such as resting tremor,muscle rigidity,bradykinesia,and postural disorder.The etiology and pathogenesis of PD are complex and related to a variety of factors.The current pathogenesis is related to mitochondrial dysfunction,oxidative stress,neuroinflammatory response,apoptosis,and autophagy.The early onset of PD is occult and the rate of misdiagnosis is high.It requires a new simple,safe,and effective early diagnosis method.The current methods of early diagnosis mainly include clinical non-motor symptoms,biomarkers,and imaging examination methods.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Tipo de estudio:
Estudio diagnóstico
/
Estudio de etiología
/
Estudio de tamizaje
Idioma:
Chino
Revista:
Clinical Medicine of China
Año:
2019
Tipo del documento:
Artículo
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