Clinical characteristics and risk factors of elderly male and female CHD patients / 中华老年心脑血管病杂志

ABSTRACT

Objective To study the clinical characteristics and risk factors of elderly female CHD patients.Methods A total of 1223elderly CHD patients(493females and 730males)were included in this study.Their general clinical data and inhospital mortality were retrospectively analyzed and the risk factors for their inhospital mortality were analyzed.Results The age was significantly older,the incidence of DM,hyperlipidemia,sleep apnea sysdrome and the ratio of divorce and widowhood were significantly higher while the number of smokers and alcohol drinkers was significantly smaller in female patients than in male patients.The serum levels of LDL-C,TC,TG,FPG,apoA-Ⅰ,apoB were significantly higher,the specific volume of RBC was significantly larger while the number of RBC was significantly smaller,the serum Hb,CK-MB,EOS,Hcy,TBA,TBIL,APTT levels were significantly lower in female patients than in male patients.No significant difference was detected in inhospital mortality between female and male patients(6.7％vs 5.9％,P＞0.05).The low glomerular filtration rate was an independent predictor of inhospital mortality in elderly female patients(HR=0.894,95％CI0.808-0.990,P=0.031)while age and serum creatine kinase isozyme level were the risk factors for inhospital mortality in elderly male patients( HR=1.169,95％CI1.013-1.350,P=0.033;HR=1.008,95％CI1.002-1.013,P=0.006).Conclusion The age of elderly female CHD patients is older than that of elderly male CHD patients.The spectrum of risk factors is significantly different between elderly female and male CHD patients.It is thus necessary to further study its prognostic value.