A clinical and pathological analysis on laryngeal contact granuloma among 18 cases / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#To summarize the clinicopathologic feature and diagnostic and therapeutic experience of laryngeal contact granuloma.@*METHOD@#A retrospective study was carried out among 18 cases with this disease through careful analysis on their clinical and pathological data.@*RESULT@#All of 18 cases were male, aged 34 to 78 years,The most common symptoms were hoarseness. In general the granuloma located on the posterior of the larynx unilaterally. The histological appearances of the lesions were typical inflammatory granuloma. Little allotype cell were found in one histologic sample. Fifteen cases received surgical excision and the recurrence rate was 60% after operation. Recidivist received operation again,4 cases among these cases received antireflux therapy after operation but 3 cases recurrences again. Among those follow-up cases(3 cases), 1 case was self-cure and other 2 cases appeared no marked change during observation period.@*CONCLUSION@#Laryngeal contact granuloma predilected the middle-aged male. The localization and appearance of the granuloma is very characteristic. The correct diagnosis can be established by clinical examination alone, but the histological examination is necessary in order to avoid missed diagnosis. There is a high recurrence rate after operation and the effect of antireflux therapy need further research.