A Case of Pure Red Cell Aplasia Associated with Angioimmunoblastic T-cell Lymphoma / Journal of the Korean Cancer Association, 대한암학회지
Cancer Research and Treatment
; : 115-117, 2010.
Article
en En
| WPRIM
| ID: wpr-74857
Biblioteca responsable:
WPRO
ABSTRACT
Pure red cell aplasia is a bone marrow failure characterized by a progressive normocytic anemia and reticulocytopenia without leucopenia and thrombocytopenia. It is associated with various hematologic diseases. However, pure red cell aplasia with angioimmunoblastic T cell lymphoma has rarely been reported. Here we describe a 43-year-old woman with pure red cell aplasia associated with angioimmunoblastic T-cell lymphoma. She had severe anemia (hemoglobin 6.9 g/dL) and a low reticulocyte count (0.2%). Direct and indirect Coombs' tests were positive. A CT scan of the abdomen revealed marked hepatosplenomegaly and small multiple lymphadenopathies. A bone marrow biopsy revealed focal infiltration of abnormal lymphoid cells and absence of red cell precursors. Splenic biopsy was compatible with angioimmunoblastic T-cell lymphoma. Ultimately, diagnosis of pure red cell aplasia associated with angioimmunoblastic T-cell lymphoma was made. After initiating CHOP therapy, the patient achieved complete remission, which was accompanied, shortly thereafter, by a rise in hemoglobin levels which finally returned to normal.
Palabras clave
Texto completo:
1
Índice:
WPRIM
Asunto principal:
Trombocitopenia
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Biopsia
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Médula Ósea
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Hemoglobinas
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Prueba de Coombs
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Linfocitos
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Linfocitos T
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Linfoma de Células T
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Aplasia Pura de Células Rojas
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Recuento de Reticulocitos
Límite:
Adult
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Female
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Humans
Idioma:
En
Revista:
Cancer Research and Treatment
Año:
2010
Tipo del documento:
Article