The effect of the expression and influence of MMP-9 on prognosis of nasal polyps / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 840-845, 2009.
Artículo
en Chino
| WPRIM
| ID: wpr-748633
ABSTRACT
OBJECTIVE@#To study the expression of MMP-9 and eosinophils in nasal polyps and its influence on the prognosis.@*METHOD@#Study the expression of MMP-9 and EOS on the tissue of nasal polyps of patients who were cured or recurrent and normal nasal mucosa (NM) by immunohistochemistry and HE staining.@*RESULT@#In the patients of recurrent group (Group B), the expression of MMP-9 was much stronger than that of good prognosis group (Group A) and NM. The MMP-9 was stronger in the eosinophil nasal polyps than that of non-eosinophil groups. The percentage of EOS in Group A was 16.67%, while 62.50% in the Group B.@*CONCLUSION@#The stronger expression of MMP-9 on Group B and eosinophil group indicated that MMP-9 might affect the prognosis of nasal polyps through inducing the number of EOS in the mucosa. MMP-9 may be one of the risk factors for the relapse of nasal polyps.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Patología
/
Pronóstico
/
Recurrencia
/
Estudios de Casos y Controles
/
Pólipos Nasales
/
Metaloproteinasa 9 de la Matriz
/
Diagnóstico
/
Eosinófilos
/
Metabolismo
/
Mucosa Nasal
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Año:
2009
Tipo del documento:
Artículo
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