Expression and significance of gene Rad52 in nasopharyngeal carcinoma / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
;
(24): 486-489, 2014.
Artículo
en Chino
| WPRIM
| ID: wpr-749322
ABSTRACT
OBJECTIVE@#To investigate the expression and clinical significance of Rad52, a homologous recombination repair gene, in tissues of nasopharyngeal carcinoma (NPC).@*METHOD@#The expression of Rad52 was detected with three-step immunohistochemistry technique in tissues of 38 NPC patients and which have the corresponding paracancerous tissues. All of the Rad52 expression and clinical data (gender, age, clinical stage ) were compared and analyzed to conclude the relationship between them.@*RESULT@#The Rad52 expressions were significantly different from NPC tissues to peri-NPC tissues (P 0.05). The expression of Rad52 influenced the survival time of NPC patients significantly (P < 0.05).@*CONCLUSION@#The Rad52 expression can be a useful prognostic and treatment factor for NPC patients.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Carcinoma
/
Regulación Neoplásica de la Expresión Génica
/
Neoplasias Nasofaríngeas
/
Tasa de Supervivencia
/
Proteína Recombinante y Reparadora de ADN Rad52
/
Carcinoma Nasofaríngeo
/
Metabolismo
/
Estadificación de Neoplasias
Tipo de estudio:
Estudio pronóstico
Límite:
Adulto
/
Femenino
/
Humanos
/
Masculino
Idioma:
Chino
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Año:
2014
Tipo del documento:
Artículo
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