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Expression and significance of gene Rad52 in nasopharyngeal carcinoma / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery ; (24): 486-489, 2014.
Artículo en Chino | WPRIM | ID: wpr-749322
ABSTRACT
OBJECTIVE@#To investigate the expression and clinical significance of Rad52, a homologous recombination repair gene, in tissues of nasopharyngeal carcinoma (NPC).@*METHOD@#The expression of Rad52 was detected with three-step immunohistochemistry technique in tissues of 38 NPC patients and which have the corresponding paracancerous tissues. All of the Rad52 expression and clinical data (gender, age, clinical stage ) were compared and analyzed to conclude the relationship between them.@*RESULT@#The Rad52 expressions were significantly different from NPC tissues to peri-NPC tissues (P 0.05). The expression of Rad52 influenced the survival time of NPC patients significantly (P < 0.05).@*CONCLUSION@#The Rad52 expression can be a useful prognostic and treatment factor for NPC patients.
Asunto(s)
Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Carcinoma / Regulación Neoplásica de la Expresión Génica / Neoplasias Nasofaríngeas / Tasa de Supervivencia / Proteína Recombinante y Reparadora de ADN Rad52 / Carcinoma Nasofaríngeo / Metabolismo / Estadificación de Neoplasias Tipo de estudio: Estudio pronóstico Límite: Adulto / Femenino / Humanos / Masculino Idioma: Chino Revista: Journal of Clinical Otorhinolaryngology Head and Neck Surgery Año: 2014 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Asunto principal: Carcinoma / Regulación Neoplásica de la Expresión Génica / Neoplasias Nasofaríngeas / Tasa de Supervivencia / Proteína Recombinante y Reparadora de ADN Rad52 / Carcinoma Nasofaríngeo / Metabolismo / Estadificación de Neoplasias Tipo de estudio: Estudio pronóstico Límite: Adulto / Femenino / Humanos / Masculino Idioma: Chino Revista: Journal of Clinical Otorhinolaryngology Head and Neck Surgery Año: 2014 Tipo del documento: Artículo