Gynecomastia induced by H1-antihistamine (ebastine) in a patient with idiopathic anaphylaxis
Asia Pacific Allergy
;
(4): 187-190, 2015.
Artículo
en Inglés
| WPRIM
| ID: wpr-750027
ABSTRACT
H1-antihistamine is generally a well-tolerated and safe drug. However, in resemblance with all other drugs, H1-antihistamines can also prompt adverse drug reactions (ADRs). We recently encountered the very unusual ADR of H1-antihistamine-induced gynecomastia. A 21-year-old man with idiopathic anaphylaxis was treated with ebastine (Ebastel), a second-generation H1-antihistamine, for the prevention of anaphylaxis. Three months later, the patient remained well without anaphylaxis, but had newly developed gynecomastia. Because anaphylaxis recurred after the cessation of H1-antihistamine, the preventive medication was changed to omalizumab. A few months later, his gynecomastia had entirely disappeared. Physicians should be aware of this exceptional ADR of H1-antihistamine.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Efectos Colaterales y Reacciones Adversas Relacionados con Medicamentos
/
Omalizumab
/
Ginecomastia
/
Antagonistas de los Receptores Histamínicos H1
/
Anafilaxia
Límite:
Humanos
/
Masculino
Idioma:
Inglés
Revista:
Asia Pacific Allergy
Año:
2015
Tipo del documento:
Artículo
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