The efficacy of single premedication with antihistamines for radiocontrast media hypersensitivity
Asia Pacific Allergy
;
(4): 164-167, 2016.
Artículo
en Inglés
| WPRIM
| ID: wpr-750070
ABSTRACT
BACKGROUND:
Single premedication with antihistamines for radiocontrast media (RCM) hypersensitivity is frequently used in real world at the emergent situation although its efficacy is not proven.OBJECTIVE:
To evaluate the effect of intravenous antihistamines as a premedication in general population who had experience of mild adverse reactions to iodinated RCM.METHODS:
A retrospective observational study on 14,785 subjects who had RCM-enhanced computed tomography scans between January 2014 and December 2015 in Seoul National University Hospital Gangnam Healthcare Center, Seoul, South Korea.RESULTS:
Among 453 subjects who had a history of mild RCM-induced hypersensitivity reactions, 273 subjects had a single premedication of intravenous antihistamine. When comparing antihistamine-premedication group and nonpremedication group, there is no protective effect of antihistamines on the incidence rate and severity of hypersensitivity (10.6% vs. 11.7%, p = 0.729).CONCLUSION:
The clinical efficacy of a single premedication of antihistamines for mild RCM-induced hypersensitivity was not confirmed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Premedicación
/
Incidencia
/
Estudios Retrospectivos
/
Resultado del Tratamiento
/
Medios de Contraste
/
Atención a la Salud
/
Estudio Observacional
/
Seúl
/
Antagonistas de los Receptores Histamínicos
/
Hipersensibilidad
Tipo de estudio:
Estudio de incidencia
/
Estudio observacional
/
Estudio pronóstico
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Asia Pacific Allergy
Año:
2016
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS