A Case of Sertoli-Leydig Cell Tumor / 대한산부인과학회잡지

ABSTRACT

The Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0.5% of all primary ovarian neoplasm. The majority of these tumors are benign and almost all are localized unilaterally. Sertoli-Leydig cell tumors occur predominantly in the second and third decades, rarely before puberty or after the menopause. In 40-50% of the patients, the presenting symptoms relate to clinical signs of androgenic activity. While most of the remainder are non-specific abdominal symptoms. Prognosis is generally favorable with 5-year survival rate of 70-90%. Recurrence is rare. Treatment varies with patient age, tumor stage, and differentiation from unilateral salpingo-oophorectomy and total hysterectomy concomitant with pelvic lymph node dissection. We have experienced a case of postmenopausal Sertoli-Leydig cell tumor with vaginal bleeding and so we present it with brief review of literature.