Research progress of intestinal flora and childhood allergic diseases / 国际儿科学杂志

ABSTRACT

Human health is closely related to the intestinal flora. The intestinal flora regulates the body's immune function by promoting the development of the immune system of the intestine, inducing differ-entiation of T cells, and other ways, so that it is in equilibrium, thereby avoiding or reducing the occurrence of immune-related diseases. Allergic diseases are related to incomplete development of the autoimmune system and imperfect immune control mechanisms. Moreover, the distribution and diversity of bacterial flora in chil-dren with allergies are significantly different from those in healthy children. Therefore, allergic diseases are closely related to the functional status of the intestinal flora. This review summarizes the associations and mech-anisms of common childhood allergic diseases, such as food allergies, eczema, asthma, and anaphylactoid purpura with intestinal flora.