Research Progress of Gas6 with Type 2Diabetes Mellitus and Diabetic Complications / 昆明医科大学学报
Journal of Kunming Medical University
;
(12): 119-124, 2018.
Artículo
en Chino
| WPRIM
| ID: wpr-751914
ABSTRACT
Growth arrest-specific 6, which is a member of the vitamin K-dependent protein family, is a ligand of TAM (Tyro3, Axl, Mer) belonging to the receptor tyrosine kinase family.Gas6/Axl signaling pathways are involved in pathophysiological processes of cell adhesion, migration, proliferation, apoptosis, platelet aggregation, vascular remodeling, inflammatory and immune responses. In recent years, studies found that Gas6/Axl signaling pathway, Gas6 level and the gene polymorphism of Gas6 were significantly associated with type 2 diabetes, obesity, insulin resistance and diabetic complications.This article reviews the correlation between Gas6 and type 2 diabetes and its complications
Texto completo:
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Índice:
WPRIM (Pacífico Occidental)
Idioma:
Chino
Revista:
Journal of Kunming Medical University
Año:
2018
Tipo del documento:
Artículo
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