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Effects of Geraniin on Modulating the Expression of Cbfα 1 Gene in Rabbit Osteoporotic Fracture / 昆明医科大学学报
Journal of Kunming Medical University ; (12): 1-4, 2018.
Artículo en Chino | WPRIM | ID: wpr-751920
ABSTRACT
Objective To investigate the the effects of geraniin on modulating the mRNA expression of corebinding factor α 1 (Cbfα 1). Methods The m RNA expressions of Cbfα 1 were detected by real time fluorescence quantitative PCR. Results As compared with the sham group, the expressions of Cbfα 1 mRNA were markedly suppressed in the model group, 12 and 24 w after OPF (P < 0.05). Compared with the model group, geraniin significantly increased mRNA expressions of Cbfα 1. Conclusion Geraniin can upregulate Cbfα 1 gene expression and improve the treatment for OPF.

Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico Idioma: Chino Revista: Journal of Kunming Medical University Año: 2018 Tipo del documento: Artículo

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Texto completo: Disponible Índice: WPRIM (Pacífico Occidental) Tipo de estudio: Estudio pronóstico Idioma: Chino Revista: Journal of Kunming Medical University Año: 2018 Tipo del documento: Artículo