Research progress in the prediction of SNP on radiation-induced lung injury / 实用肿瘤学杂志

ABSTRACT

Radiotherapy is an important treatment for lung cancer. However,the radiation-induced lung injury(RILI)affects some patients and also affects the efficacy of treatment. Therefore,it is very important to identify high-risk patients who may have RI-LI and take action intervention or monitoring. Although the individual difference is often explained by clinical and dosimetric,genetic factors also influence the occurrence of RILI. Currently,there are reports on the relationship between single nucleotide polymorphism (SNP)and RILI. The SNP of these specific genes may become an important predictor of RILI,and thus reduce the incidence of radia-tion-induced lung injury.