Progress on pathogenesis of capillary leak syndrome / 中国小儿急救医学

ABSTRACT

Capillary leak syndrome is a disease characterized by high permeability of vascular endo-thelium leading to anasarca,hypotension,hypoalbuminemia and hemoconcentration,It can cause multiple or-gan failure and high mortality in acute stage. Vascular endothelial hyperpermeability is the core of pathogene-sis of capillary leak syndrome. This article reviewed the latest research progress on the pathogenesis of capil-lary leak syndrome from the aspects of serological mechanism,histological changes and genetic factors.