Clinical Effects of Oral Naproxen for the Treatment of Eosinophilic Pustular Folliculitis / 대한피부과학회지
Korean Journal of Dermatology
;
: 1609-1614, 2008.
Artículo
en Coreano
| WPRIM
| ID: wpr-75413
ABSTRACT
BACKGROUND:
Eosinophilic pustular folliculitis (EPF) is characterized by erythematous patches of follicular papules and pustules that mainly involve the face. Although various treatments have been attempted for EPF, including systemic and topical steroids, dapsone and indomethacin, there is no consensus on the first choice for treatment.OBJECTIVE:
The purpose of this study was to evaluate the clinical efficacy and safety of naproxen treatment for EPF patients.METHODS:
We retrospectively reviewed the clinical records of 16 biopsy-proven EPF patients who were treated with naproxen. Initial dose of oral naproxen was 500 mg to 1,000 mg. Therapeutic effects were evaluated by 3 grades NR (no response), PR (partial remission, >50% improvement), CR (complete remission).RESULTS:
Of the 16 EPF patients, 11 patients (69%) showed either complete remission (50%) or partial remission (19%). The median time to response for good responders (CR+PR) was 1.5 weeks. Two patients (13%) had mild gastrointestinal side effects, such as indigestion, but the symptoms disappeared soon after use of a gastrointestinal protectant.CONCLUSION:
Oral naproxen may be an effective and safe treatment modality for EPF.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Esteroides
/
Indometacina
/
Naproxeno
/
Estudios Retrospectivos
/
Enfermedades Cutáneas Vesiculoampollosas
/
Dapsona
/
Consenso
/
Dispepsia
/
Eosinofilia
/
Eosinófilos
Tipo de estudio:
Guía de Práctica Clínica
/
Estudio observacional
Límite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Dermatology
Año:
2008
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS