Certain issues related to time window for neurorestoratology following spinal cord injury / 中华创伤杂志

ABSTRACT

Spinal cord injury has long been a major problem difficult to resolve in medicine, which brings heavy burdens to individuals, families and the society. Microenvironment imbalance after spinal cord injury is the main cause for poor nerve restoration. Besides, microenvironment imbalance after spinal cord injury has spatiotemporal specificity. It is necessary to accurately regulate the changes of microenvironment in different periods and clarify the therapeutic time window of different interventions to improve the therapeutic effect and reduce the related complications. However, the therapeutic time window of spinal cord injury is vague and general at present. This article mainly focused on the latest research progress in the time window of drug use, surgical operation, cell transplantation and rehabilitation for spinal cord injury, so as to provide references for clinical therapy strategies.