The Combined Effect of Physical Barriers and 5-Fluorouracil on Delayed Adjustable Strabismus Surgery

ABSTRACT

In order to prevent the formation of postoperative adhesions and delay the time of adjustment, the authors tried 5-fluorouracil and physical barriers of polytetrafluoroethylene, Interceed, Viscoat in rabbits. Fluorouracil delayed the adjustment for up to one week after surgery in three out of four eyes. Combined use of Interceed and 5-fluorouracil of addition of Viscoat could delay the adjustment for up to two weeks after surgery I one out of four eyes. Combined use of pophtetrafluoroethylene and 5-fluorouracil of addition of Viscoat could delay the adjustment for up to four weeks after surgery in four out of five eyes. In conclusion, combined use of polytetrafluoroethylene, 5-fluorouracil and Viscoat could be more helpful for delayine adjustment in rabbits.