Methodological progress of 18 F-labeled aromatic PET radiotracers / 中华核医学与分子影像杂志
Chinese Journal of Nuclear Medicine and Molecular Imaging
; (6): 499-503, 2019.
Article
en Zh
| WPRIM
| ID: wpr-755296
Biblioteca responsable:
WPRO
ABSTRACT
PET serves as one of the most advanced imaging modalities,and its development depends on the improvement of radiotracers.Among numerous positron isotopes,18 F appears to be the best radionuclide candidate for PET radiotracers by virtue of its favorable physical characteristics.18 F-labeled aromatic radiotracers have been widely investigated by researchers due to its special metabolic stability.However, the development and application of 18 F-labeled aromatic radiotracers have been limited due to lacking of radiochemical methods to obtain products with high selectivity,high radioactivity and high purity.This review focuses on the new labeling methods of 18 F-labeled aromatic radiotracers from the aspects of electrophilic and nucleophilic substitution reactions.
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Índice:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Nuclear Medicine and Molecular Imaging
Año:
2019
Tipo del documento:
Article