Advances in the effectiveness of rotavirus vaccines and its influencing factors / 中华微生物学和免疫学杂志

ABSTRACT

Rotavirus is the leading cause of acute gastroenteritis in children, and vaccines are the most effective measure to control rotavirus diarrhea. Currently, two vaccines, namely Rotarix and RotaTeq, are widely used worldwide. In addition, several vaccines are licensed in some countries. This review summa-rized the effectiveness of licensed rotavirus vaccines and the potential factors which might affect the effective-ness of these vaccines. In addition, progress in novel vaccine candidates in development was also included in this review.