Progress in norovirus research and vaccine development / 中华微生物学和免疫学杂志

ABSTRACT

Norovirus is one of the leading causes of acute non-bacterial gastroenteritis. Emergence of new genotypes due to frequent genetic recombination and antigenic drift increases the prevalence of noro-virus infection worldwide. Norovirus infection has become a global public health concern. This review fo-cused on disease burden, vaccine research, cell culture and animal models regarding norovirus infection.