Matrix Metalloproteinase-1 and Tissue Inhibitor of Metalloproteinase-1 levels in Exudative Pleural Effusions / 결핵및호흡기질환
Tuberculosis and Respiratory Diseases
;
: 517-521, 2005.
Artículo
en Coreano
| WPRIM
| ID: wpr-75627
ABSTRACT
BACKGROUND:
The balances of the proteinases and antiproteinases system have been implicated in the pathogenesis of various exudative pleural effusions. The aim of this study was to examine the matrix metalloproteinase-1 (MMP-1) and tissue inhibitor of metalloproteinase-1 (TIMP-1) levels in exudative pleural effusions.METHODS:
The study included 33 tuberculous effusions, 17 malignant, and 5 transudates. The pleural levels of MMP-1 and TIMP-1 were determined using a commercially available ELISA assay.RESULTS:
The group of tuberculous effusions showed higher pleural MMP-1 levels than the malignant and transudates. The pleural TIMP-1 levels of the tuberculous and malignant effusions were higher than the transudates.CONCLUSION:
Elevated pleural MMP-1 and TIMP-1 levels were found in tuberculous effusions.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Péptido Hidrolasas
/
Derrame Pleural
/
Ensayo de Inmunoadsorción Enzimática
/
Inhibidor Tisular de Metaloproteinasa-1
/
Metaloproteinasa 1 de la Matriz
/
Exudados y Transudados
Idioma:
Coreano
Revista:
Tuberculosis and Respiratory Diseases
Año:
2005
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS