Mass spectrometry based proteomics, background, status and future needs
Protein & Cell
;
(12): 641-647, 2012.
Artículo
en Inglés
| WPRIM
| ID: wpr-757226
ABSTRACT
An overview of the background for proteomics and a description of the present state of art are given with a description of the main strategies in proteomics. The advantages and limitations of the two major strategies, 2D-gel based and LC-MS based, are discussed and a combination for the two, CeLC-MS is described. A number of challenging problems which have been solved using different proteomics strategies including the advantage of organell enrichment or modifications specific peptide isolation to get deeper into the proteome are described. Finally the present status and future needs discussed.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Péptidos
/
Fosforilación
/
Espectrometría de Masas
/
Electroforesis en Gel Bidimensional
/
Química
/
Cromatografía Líquida de Alta Presión
/
Isoformas de Proteínas
/
Proteoma
/
Proteómica
Idioma:
Inglés
Revista:
Protein & Cell
Año:
2012
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS