Flavestin K, An Isoprenylated Stilbene from the Leaves of Macaranga recurvata Gage
Natural Product Sciences
;
: 244-247, 2019.
Artículo
en Inglés
| WPRIM
| ID: wpr-760565
ABSTRACT
A new isoprenylated stilbene, flavestinK (1) together with two known isoprenylated stilbenes, flavestin B (2), flavestin G (3), and two isoprenilated flavanones, 4-O-methyl-8-isoprenylnaringenin (4) and 8-isoprenyl-5,7-dihydroxyflavanone (5) were isolated from the leaves of Macaranga recurvata Gage. All of the structures have been determined based on HRESIMS, 1D and 2D NMR spectral data. All of the isolated compounds were evaluated for their cytotoxicity against three human cancer cells (HeLa, T47D and WiDr). Compound 1 showed higher activity than doxorubicin against HeLa cells with IC₅₀ value of 13.1 µg/mL.
Texto completo:
Disponible
Índice:
WPRIM (Pacífico Occidental)
Asunto principal:
Estilbenos
/
Células HeLa
/
Doxorrubicina
/
Euphorbiaceae
/
Flavanonas
Límite:
Humanos
Idioma:
Inglés
Revista:
Natural Product Sciences
Año:
2019
Tipo del documento:
Artículo
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